C22.1 Description: Intrahepatic bile duct carcinoma Exclude1:
malignant neoplasm of hepatic duct (C24.0)
Inclusion Term:
Cholangiocarcinoma
↓
C22 Description: Malignant neoplasm of liver and intrahepatic bile ducts Exclude1:
malignant neoplasm of biliary tract NOS (C24.9)
secondary malignant neoplasm of liver and intrahepatic bile duct (C78.7)
Use Additional Code:
code to identify:
alcohol abuse and dependence (F10.-)
hepatitis B (B16.-, B18.0-B18.1)
hepatitis C (B17.1-, B18.2)
↓
C15-C26 Description: Malignant neoplasms of digestive organs (C15-C26) Exclude1:
Kaposi's sarcoma of gastrointestinal sites (C46.4)
Exclude2:
gastrointestinal stromal tumors (C49.A-)
↓
C00-D49 Description: Neoplasms Notes:
Functional activity
All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
Morphology [Histology]
Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
Primary malignant neoplasms overlapping site boundaries
A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
Malignant neoplasm of ectopic tissue
Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).